contact
lens care
The
Latest Research in Contact Lens Care
BY
SUSAN J. GROMACKI, OD, MS, FAAO
The contact lens solution industry is continuously
working to provide better products. More efficacious and biocompatible solutions
lead to cleaner and more comfortable lenses, resulting in more
satisfied patients and practitioners. Better technology benefits all parties; it
is good business.
Here are research highlights of the most recent American Academy
of Optometry and American Optometric Association meetings. Study sponsors appear
in parentheses at the end of each summary. Consider the research source when evaluating
outcomes.
Robboy and China After one hour of wear, 14 of 19 dry eye subjects
preferred PureVision lenses pre-treated with ReNu with MoistureLoc (Bausch &
Lomb); five subjects preferred O2Optix/Aquify 5-minute MPS (CIBA Vision).
(B&L)
Reindel et al On average, 152 contact lens wearers reported improved
comfort after two weeks and one, two and three months when using ReNu with MoistureLoc
as compared with their habitual solution. (B&L)
Garofalo et al Patients rated Alcon's test disinfection formula
superior to ReNu MultiPlus MPS (B&L) in comfort and satisfaction. Lens deposit
and surface evaluation scores were also better with the test formulation. (Alcon)
Carey et al There are differences in uptake of solutions when
combining use of alexidine, polyhexanide (PHMB) or polyquaternium-1 (Polyquad) with
different lens materials (Soflens 66 [B&L], Acuvue 2 and Acuvue Advance [Vistakon]).
Lenses cycled with the Polyquad-based product showed minimal uptake into lenses;
corneal staining was low for all materials tested. (Alcon)
Stauffer et al Using a no-rub/rinse regimen on Acuvue 2,
Alcon's new formulation and Opti-Free Express exceeded ReNu MultiPlus, Complete
Moisture Plus (AMO), Aquify and ReNu with MoistureLoc in removal of lysozyme. (Alcon)
Garofalo et al Subjects who wore Group I silicone hydrogel or
Group II hydrogel lenses soaked in ReNu MultiPlus, Solo-care (CIBA) or Complete
Moisture Plus exhibited asymptomatic, statistically significant corneal staining
during the first few hours of lens wear; not with Opti-Free Express. (Alcon)
Groemminger and Dobie After exposure to harsh denaturation conditions,
ReNu with MoistureLoc enabled more lysozyme to remain in its native (active) form
than did Opti-Free Express, Solo-care Aqua or Complete Moisture Plus. (B&L)
Rosenthal et al Not rinsing lenses prior to disinfection with
multipurpose solutions results in less efficacious cleaning. Opti-Free Express displayed
more antimicrobial effects than did Solo-care, Complete Moisture Plus or CyClean
(Sauflon Pharmaceuticals). (Alcon)
Ketelson et al Pre-soaking/treating Acuvue Advance lenses
in Opti-Free Express may improve wettability and comfort. (Alcon)
Borazjani et al ReNu MultiPlus and ReNu with MoistureLoc showed
higher cumulative log reduction values in microorganisms than did Opti-Free Express,
Solo-care Plus, Complete and Complete Moisture Plus. (B&L)
Gruss et al Opti-Free Express exacerbates the alteration of tear
protein composition, while Complete MPS restores tears similar to a non-lens-wearing
state.
Lievens et al Of ReNu, Opti-Free Express and Complete, only ReNu
showed statistically or nearly significant adverse changes in tear break up time,
bulbar conjunctival injection and corneal sensitivity.
Paugh et al A carboxymethylcellulose drop, instilled before lens
insertion, may reduce corneal staining resulting from disinfection with a PHMB-based
multipurpose solution. (Allergan)
Dr. Gromacki is in group
practice in Burke, Virginia, and has served as a faculty member at the University
of Michigan Department of Ophthalmology and Visual Sciences.
Contact Lens Spectrum, Issue: October 2005