Article Date: 1/1/2014

Dry Eye Dx and Tx
Dry Eye Dx and Tx

The Hormone-Dry Eye Connection, Part 1



Sex hormones have a long-recognized impact on tear production and ocular surface health (Rocha et al, 2013). More recently, research has also exposed the influence of non-sex hormones on the ocular surface, particularly in regard to tear production (Gadaria-Rathod et al, 2013).

Sex Hormones and Dry Eye

Researchers have conducted numerous studies exploring the influence of sex hormones on tear function and the ocular surface (Sullivan D, Yamagami et al, 2002; Sullivan B et al, 2002; Sullivan D, Schaumberg et al, 2002; Suzuki et al, 2002). Some of the issues addressed by this research include:

Thyroid Hormones and Dry Eye

Thyroid disease has long been identified as a potential risk factor for dry eye (Karsh et al, 1980):

For references, please visit and click on document #218.

Dr. Townsend practices in Canyon, Texas, and is an adjunct professor at the University of Houston College of Optometry. He is president of the Ocular Surface Society of Optometry and conducts research in ocular surface disease, lens care solutions, and medications. He is also an advisor to Alcon, B+L, CooperVision, Tearlab Corporation, and Vistakon. Contact him at

Contact Lens Spectrum, Volume: 29 , Issue: January 2014, page(s): 18