eye dx and tx
WILLIAM TOWNSEND, OD
A frustrating facet of managing ocular surface
disease is our inability to directly visualize when the glandular tissue that secretes
the various components of the tears is damaged or compromised.
how a better knowledge of the true state of the diseased tissue would impact your
decision making and recommendations.
Evaporative dry eye commonly results from compromised meibomian
gland function. This is one area in which we can now actually evaluate the number
and quality of oil-secreting glands that reside within the eyelids.
History of Transillumination
With biomicroscopy you can directly examine the yellow lines under
the tarsal conjunctiva, sometimes called the piano key pattern, that are the meibomian
glands. In 1982, Jester et al described the diagnostic technique of transillumination
and photography of meibomian gland changes in rabbits. Robin et al (1985) showed
the value of this procedure in evaluating meibomian gland dysfunction in humans.
then, several studies have demonstrated the value of transillumination as a means
of determining the status of the meibo-
mian glands. Although instruments that
permit transillumination of large areas of the lids have been devised and used in
studies, none are commercially available.
Happily, virtually all eyecare practitioners already own an instrument
that is useful for performing this technique: A standard transilluminator at the
biomicroscope. Using it is a simple and easily mastered procedure that yields very
important information about the status of these structures.
Performing the Procedure
To perform transillumination, position the patient at the slit
lamp in the conventional manner. Next position the transilluminator just below the
lash line of the lower lid and use the instrument to evert and retroilluminate the
lid (Figure 1). This allows light to pass through the lid, revealing the outlines
of the meibomian glands. At this point, turn off slit lamp illumination to enhance
visualization. You can see areas of partial or total loss of glandular structure
using this technique (Figure 2).
Chronic inflammation and dysfunction can result in partial or
total loss of meibomian glands. In most cases, dropout initially occurs in the distal
portion of the gland, farthest from the orifice. Over time, tissue destruction progresses
until only the proximal portion of the gland remains (proximal condensation). We
find that external ocular photo-documentation (CPT-92285) is very useful in monitoring
the stability or progression of this condition.
Worth the Effort
Meibomian gland transillumination is an easily mastered technique
that helps to predict or explain clinical signs and symptoms. Consider adding it
to your battery of tests in assessing patients who have signs and symptoms of ocular
surface disease. It can help identify patients who have little potential for improvement
of their meibomian gland disease because the structures are severely damaged or
To obtain references for this article, please visit http://www.clspectrum.com/references.asp
and click on document #134.
Dr. Townsend is in private
practice in Canyon, Texas, and is a consultant at the Amarillo VA Medical Center.
E-mail him at email@example.com.
Contact Lens Spectrum, Issue: January 2007