Contact Lens Spectrum


January 2012

Document #194



(p. 12) Research Review: Corneal Infiltrates: Managing Risks With Soft Lens Wear

By Loretta Szczotka-Flynn,OD, PhD, FAAO, and Robin Chalmers, OD, FAAO

1. Josephson J. Infiltrative keratitis in hydrogel lens wearers. Int Contact Lens Clin. 1979;6:223-241.

2. Hine N. Hypersensitivity with silicone hydrogels: material or solution effect? Available at:

3. Kislan TP, Hom MM. Corneal infiltrates with multipurpose solutions and contact lens combinations. Invest Ophthalmol Vis Sci. 2010;51(suppl):E-Abstract 3424.

4. Sacco A. Contact Lens-Associated Infiltrative Keratitis and Multipurpose Solutions. Contact Lens Spectrum. April 2011. Available at:

5. Bausch + Lomb. FDA summary of safety and effectiveness data for a supplemental premarket application for balafilcon A hydrophilic contact lenses. 2001.

6. Chalmers RL, Schein MJ, Katz J, et al. Risk factors for corneal infiltrates with continuous wear of contact lenses. Optom Vis Sci. 2007;84:573-579.

7. Ciba. Summary of safety and effectiveness data for 30-day wear of lotrafilcon A. 2011.

8. Szczotka-Flynn L, Diaz-Insua M. Risk of corneal inflammatory events with silicone hydrogel and low-Dk hydrogel extended contact lens wear: a meta-analysis. Optom Vis Sci. 2007;125:1-5.

9. Carnt NA, Evans VE, Naduvilath TJ. Contact lens-related adverse events and the silicone hydrogel lenses and daily wear care system used. Arch Ophthalmol. 2009;127:1616-1623.

10. Chalmers R. What have pre- and post-approval studies shown about contact lens-related inflammatory events? Eye & Contact Lens. 2007;33:388-391.

11. Chalmers RL, McNally J, Kern J. Multi-center case control study of the role of lens materials and care products on the development of corneal infiltrates. Optom Vis Sci. 2011 (in press; accepted Oct. 16, 2011).

12. Chalmers RL, Mitchell GL, Lam DY, et al. Age and other risk factors for corneal infiltrative and inflammatory events in young soft contact lens wearers from the Contact Lens Assessment in Youth (CLAY) Study. Invest Ophthalmol Vis Sci. 2011;52:6690-6696.

13. du Toit R, John T, Sweeney D, Kalliris A, Tahhan N, Papas E. Association of age, gender and ethnicity with the incidence of adverse responses with extended wear of silicone hydrogel lenses. Optom Vis Sci. 2002;79:12s.

14. Szczotka-Flynn L, Lass JH, Sethi S, et al. Risk factors for corneal infiltrative events during continuous wear of silicone hydrogel contact lenses. Invest Ophthalmol Vis Sci. 2010;51:5421-5430.

15. McNally JJ, Chalmers RL, McKenney CD, Robirds S. Risk factors for corneal infiltrative events with 30-night continuous wear of silicone hydrogel lenses. Eye Contact Lens. 2003;29(1 suppl);S153-S156.

16. Chalmers RL, Keay L, Long B, Bergenske P, Giles T, Bullimore MA. Risk factors for contact lens complications in US clinical practices. Optom Vis Sci. 2010;87:725-735.

17. Willcox M, Sharma S, Naduvilath TJ, Sankaridurg PR, Gopinathan U, Holden BA. External ocular surface and lens microbiota in contact lens wearers with corneal infiltrates during extended wear of hydrogel lenses. Eye Contact Lens. 2011;37:90-95.

18. Efron N, Morgan PB, Hill EA, Raynor MK, Tullo AB. Incidence and morbidity of hospital-presenting corneal infiltrative events associated with contact lens wear. Clin Exp Optom. 2005;88:232-239.

19. Radford CF, Minassian D, Dart JK, Stapleton F, Verma S. Risk factors for nonulcerative contact lens complications in an ophthalmic accident and emergency department: a case-control study. Ophthalmology. 2009;116:385-392.

20. Schein OD, McNally JJ, Katz J, et al. The incidence of microbial keratitis among wearers of a 30-day silicone hydrogel extended-wear contact lens. Ophthalmology. 2005;112:2172-2179.



(p. 17) Contact Lens Design & Materials: Better Vision With Contact Lenses

By Ronald K. Watanabe, OD, FAAO

1. Hong X, Himebaugh N, Thibos LN. On-eye evaluation of optical performance of rigid and soft contact lenses. Optom Vis Sci. 2001;78:872-880.

2. Dorronsoro C, Barbero S, Llorente L, Marcos S. On-eye measurement of optical performance of rigid gas permeable contact lenses based on ocular and corneal aberrometry. Optom Vis Sci. 2003;80:115-125.



(p. 18) Dry Eye Dx and Tx: The Role of Mucins in Ocular Health

By Katherine M. Mastrota, MS, OD, FAAO

1. Nichols KK, Foulks GN, Bron AJ, et al. The International Workshop on Meibomian Gland Dysfunction: Executive Summary. Invest Ophthalmol Vis Sci. 2011;52:1917-2085.

2. Mantelli F, Argueso P. Functions of ocular surface mucins in health and disease. Curr Opin Allergy Clin Immunol. 2008;8:477-483.

3. Wang IJ, Yu CJ, Hu, FR. Alteration of ocular surface mucins in MU5AC-DTA transgenic mice. Molecular Vision. 2009;15:108-119.

4. Inatomi T, Spurr-Michaud S, Tisdale AS, Zhan Q, Feldman ST, Gipson IK. Expression of secretory mucin genes by human conjunctival epithelia.  Invest Ophthalmol Vis Sci. 1996;37:1684-1692.

5. Inatomi T, Spurr-Michaud S, Tisdale AS, Gipson IK. Human corneal and conjunctival epithelia express MUc1mucin. Invest Ophthalmol Vis Sci.1995;36:1818-1827.

6. Gibson IK. Distribution of mucins at the ocular surface. Exp Eye Res. 2004;78:379-388.

7. De Nadal E, Real FX, Ponas F. Mucins, osmosensors in eukaryotic cells? Trends Cell Biol. 2007;17:5871-5874.



(p. 19) Contact Lens Care & Compliance: The Handling and Care of Scleral GP Contact Lenses, Part 2

By Susan J. Gromacki, OD, MS, FAAO

1. DeNaeyer G.  Personal communication, July 29-August 4; November 2, 2011.

2. Van der Worp E. Managing scleral lens wear. In: A Guide to Scleral Lens Fitting, Scleral Lens Education Society, 2010:40-41.

3. DeNaeyer G. Contact Lens Spectrum Special Edition 2011:

4. Accessed November 2, 2011.



(p. 34) Keratoconus Fitting With Specialty Soft Lenses

By S. Barry Eiden, OD, FAAO, & Gregory W. DeNaeyer, OD, FAAO

 1. de Brabander J, Chateau N, Marin G, et al. Simulated optical performance of custom wavefront soft contact lenses for keratoconus. Optom Vis Sci. 2003;80:637-643.

2. Holden BA, Zantos SG. On the conformity of soft lenses to the shape of the cornea. Am J Optom Physiol Opt. 1981;58:139-143.

3. Zadnik K, Barr JT, Edrington TB, et al. Baseline findings in the Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study. Invest Ophthalmol Vis Sci. 1998;39:2537-2546.

4. Marsack JD, Parker KE, Applegate RA. Performance of wavefront-guided soft lenses in three keratoconus subjects. Optom Vis Sci. 2008;85:1172-1178.

5. Guirao A, Cox IG, Williams DR. Method for optimizing the correction of the eye’s higher-order aberrations in the presence of dencentrations. J Opt Soc Am (A). 2002;19:126-128.

6. Marsack JD, Parker KE, Niu Y, et al. On-eye performance of custom wavefront-guided soft lenses in a habitual soft lens-wearing keratoconic patient. J Refract Surg. 2007;23:960-904.

7. Chen M, Sabesan R, Ahmad K, Yoon G. Correcting anterior aberration and variability of lens movements in keratoconic eyes with back-surface customized soft contact lenes. Opt Lett. 2007;32:3203-3205.



(p. 38) Compliance Before, During and After Contact Lens Wear

By Sheila Hickson-Curran, BSc(Hons), MCOptom, FAAO

1. Dietlein TS, Jordan J, Dinslage S, Krieglstein GK. What do glaucoma specialists know about their patients? Graefes Arch Clin Exp Ophthalmol. 2006;244:859-862.

2. Cramer JA. A systematic review of adherence with medications for diabetes. Diabetes Care. 2004;27:1218-1224.

3. Bocuzzi SJ, Foltz SH, Omar MA, Kahler KH, Gutierrez B. Adherence and persistence associated with the pharmacologic treatment of osteoporosis. Osteoporos Int. 2005;16(suppl 3):S24.

4. Hickson-Curran S, Chalmers RL, Riley C. Patient attitudes and behavior regarding hygiene and replacement of soft contact lenses and storage cases. Cont Lens Anterior Eye. 2011, doi:10.1016/j.clae.2010.12.005.

5. Radford CF, Minassian D, Dart JK, et al. Risk factors for nonulcerative contact lens complications in an ophthalmic accident and emergency department: a case-control study. Ophthalmol. 2009;116:385-392.

6. Dumbleton K, Woods C, Jones L, et al. Patient and practitioner compliance with silicone hydrogel and daily disposable lens replacement in the United States. Eye Contact Lens. 2009;35:164-171.

7. Dumbleton K, Richter D, Woods CA, et al. Relationship between compliance with lens replacement and contact lens-related problems in silicone hydrogel wearers. Contact Lens Ant Eye. 2011; doi:10.1016/j.clae.2011.03.001.

8. Dumbleton K, Woods C, Jones L, Fonn D. Comfort and vision with silicone hydrogel lenses: Effect of compliance. Optom Vis Sci. 2010;87:421-425.

9. Yeung KK, Forister JFY, Forister EF, et al. Compliance with soft contact lens replacement schedules and associated contact lens-related ocular complications: the UCLA Contact Lens Study. Optometry. 2010;81:598-607.

10. Hickson-Curran SB, Alford J. Silicone hydrogel replacement frequency: Impact on frequency of scheduled and unscheduled clinic visits. Optom Vis Sci. 2010;87: E-Abstract 105870.



(p. 44) Practice Pearls: Will You Be One of the 8 Percent In 2012?

By Jason R. Miller, OD, MBA, FAAO

1. Opinion Corporation of Princeton, NJ. Accessed December 8, 2011.



(p. 47) Pediatric and Teen CL Care: Improving More Than Vision With a Contact Lens Fitting

By Mary Lou French, OD, MEd, FAAO

1. Walline JJ, Jones LA, Chitkara M, et al. The adolescent and child health initiative to encourage vision empowerment (ACHIEVE) study design and baseline data. Optom Vis Sci. 2006;83:37-45.

2. Walline JJ, Jones LA, Sinnott L, et al., Randomized trial of the effect of contact lens wear on self-perception in children. Optom Vis Sci. 2009;86:222-232.



(p. 48) Treatment Plan: Treating and Managing Calcific Changes in the Cornea

By William L. Miller, OD, PhD, FAAO

1. Wolf MD, Lichter PR, Ragsdale CG. Prognostic factors in the uveitis of juvenile rheumatoid arthritis. Ophthalmol. 1987;94:1242-1248.

2. Sharma N, Mannan R, Sinha R, et al. Excimer laser phototherapeutic keratectomy for the treatment of silicone oil-induced band-shaped keratopathy. Eye Contact Lens. 2011;37:282-285.

3. Ozdek S, Yuksel N, Gurelik G, Hasanreisoglu B. High-density silicone oil as an intraocular tamponade in complex retinal detachments. Can J Ophthalmol. 2011;46:51-55.

4. Anderson DF, Prabhasawat P, Alfonso E et al. Amniotic membrane transplantation after the primary surgical management of band keratopathy. Cornea. 2001;20:354-361.

5. Im SK, Lee KH, Yoon KC. Combined ethylenediaminetetraacetic acid chelation, phototherapeutic keratectomy and amniotic membrane transplantation for treatment of band keratopathy. Korean J Ophthalmol. 2010;24:73-77. Epub 2010 Apr 6.

6. Jhanji V, Rapuano CJ, Vajpayee RB. Corneal calcific band keratopathy. Curr Opin Ophthalmol. 2011;22:283-289.

7. de Ortueta D, Schreyger F, Baatz H. Band keratopathy: a modified treatment. Eur J Ophthalmol. 2006;16:618-620.



(p. 50) Reader and Industry Forum: A Novel GP Contact Lens for Presbyopia

By Dorothy Win-Hall, OD

1. Studebaker J. Soft multifocals: practice growth opportunity. Contact Lens Spectrum. June 2009, pp. 40-43.



(p. 52) Reader and Industry Forum: Overcoming Cost Objections to Daily Disposable Lens Wear

By Peter D. Bergenske, OD, FAAO

1. Third-party industry report. Jan-Feb 2011.

2. Survey of 109 wearers of Dailies AquaComfort Plus lenses; Ciba Vision data on file, 2009.



End Document #194