Happy New Year! A tradition of Contact Lens Spectrum is to select a contact lens event of the year; this is something that we report in our January issue each year as a nice way to cap the prior year as we go forward into the New Year. The event is something that is significantly noteworthy (good or bad) in the field of contact lenses, and it is typically a challenge to narrow down to a single event.
The International Association of Contact Lens Educators (IACLE) will mark its 40th year with anniversary events in the United Kingdom, the Philippines, Colombia, and the United States during 2019. Celebrations will be held at the British Contact Lens Association Clinical Conference & Exhibition in Manchester (May 30 to Jun. 1), the Asia Pacific Optometric Congress in Manila (Jun. 17 20), the FEDOPTO (Colombian Federation of Optometrists) Congress in Bogotá (Aug. 8 to 10), and at the joint Academy 2019 and 3rd World Congress of Optometry in Orlando, FL (Oct. 23 to 28). More details of IACLE’s 40th anniversary celebrations—including special events, presentations, awards, and interactive exhibits—will be available throughout 2019.
Ron Walker, Former AllAboutVision.com Publisher, Joins Innovega
Innovega Inc. announced the addition of longtime eyecare publisher Ron Walker to its team.
In 1999, Mr. Walker co-founded AllAboutVision.com, a website educating consumers about eye health and vision correction, and served as its publisher for 18 years. From 1985 to 1992, he was publisher of Contact Lens Spectrum and a partner in Viscom Publications, which also published Eyecare Business. In 1997, Mr. Walker co-founded Contact Lenses Today in partnership with Dr. Joseph Barr and Contact Lens Spectrum. He began his career in 1977 with an advertising and PR firm specializing in retail optical, and he also held editorial and sales positions with Optometric Management, Ophthalmology Management, and Contact Lens Forum magazines.
Mr. Walker serves on the U.S. Advisory Committee of Optometry Giving Sight and assists the Contact Lens Manufacturers Association with various online educational efforts.
PEN Offers Scleral Lens Workshop
Primary Eyecare Network (PEN), a division of ABB Optical Group, is offering a workshop on scleral lenses on Feb. 9 from 8:00 a.m. to 1:00 p.m. in Concord, CA. This hands-on, comprehensive workshop is designed to cover all bases of scleral lenses from fitting to billing and will be led by optometrist Melissa Barnett, OD. Additionally, the workshop will include a scleral wet lab that will focus on patient fitting, application and removal training, and troubleshooting.
The event is pending approval for two hours’ worth of continuing education credits from the Council on Optometric Practitioner Education (COPE).
iChek announced the addition of Steve Martin to its advisory board. Mr. Martin is a nationally recognized and accomplished executive and entrepreneur with more than 30 years of experience in the optical and medical device industry. He is the founder of Ciba Vision Optics, now part of Alcon and Ciba Vision Ophthalmics, now part of Novartis.
Imprimis Pharmaceuticals, Inc. Completes Name Change to Harrow Health, Inc.
Harrow Health, Inc. (formerly known as Imprimis Pharmaceuticals, Inc.) announced that it has formally changed its name. Harrow Health’s businesses and subsidiaries each have strong brand equity and will continue to operate under the Harrow Health corporate umbrella using their existing names. This includes Harrow Health’s wholly-owned subsidiaries ImprimisRx, an ophthalmology pharmaceutical compounding business, and Park Compounding. Harrow Health’s equity interests and royalty-rights in Eton Pharmaceuticals, Surface Pharmaceuticals, Melt Pharmaceuticals, Mayfield Pharmaceuticals, and Radley Pharmaceuticals remain in Harrow Health as well.
If you practice myopia control using atropine, what percentage do you use?
This image shows a conjunctival nevus in an adolescent male that has been present for many years and shows varying degrees of pigmentation and small cyst formation. While benign lesions such as this may enlarge over time, melanotic malignant transformation should always be considered and ruled out. Baseline photography of lesions is necessary to monitor for changes over time.
We thank Dr. Lundquist for this image and welcome photo submissions from our other readers! It is easy to submit a photo for consideration for publishing in Contact Lenses Today. Simply visit http://www.cltoday.com/upload/upload.aspx to upload your image. Please include a detailed explanation of the photo and your full name, degree or title, and city/state/country.
S. Barry Eiden, OD
It’s All About Achieving "Nothing": Can Contact Lenses Achieve an Experience Similar to that of an Emmetrope?
Let’s be frank, the only purpose of a contact lens used for the correction of refractive error is to provide clear vision. Beyond that, practitioners don’t want contact lenses to do anything. As George Costanza of the Seinfeld show said: "Jerry, this show is about nothing!" An optimal contact lens would do nothing other than compensate for patients’ refractive error and provide clear vision. It should not impact eye health, and it should not impact patients’ ocular comfort. It should, in essence, "do nothing."
A recent study was published that assessed comfort, vision, and adverse events during daily disposable contact lens wear relative to emmetropes and spectacle wearers.1 Participants in the three-month study either wore one of five daily disposable contact lenses (n = 201), were full-time spectacle wearers with no history of contact lens wear (n = 34), or were emmetropic non-contact lens wearers (n = 40). Vision quality and comfort were assessed at the beginning and end of the day (1 to 10). Corneal infiltrative events were recorded. Between-group comparisons were made using a linear mixed model and literature estimates of clinical significance.
Results indicated that Initial comfort among emmetropes (mean ± 95% confidence interval, 8.0 ± 0.5) was not significantly different from any of the contact lens types (range, 7.2 ± 0.4 to 8.0 ± 0.4, all P > 0.06) or spectacle wearers (7.3 ± 0.5, P = 0.45). Comfort deteriorated during the day in all groups (P < 0.05). End-of-day comfort for emmetropes (7.3 ± 0.6) was significantly better other than for lenses B (5.7 ± 0.6, P < 0.001) and D (6.2 ± 0.5, P = 0.01). Vision quality for emmetropes (8.6 ± 0.5) was better than for spectacle wearers (7.8 ± 0.5, P = 0.04) and for lenses A (7.6 ± 0.4, P = 0.003) and B (7.5 ± 0.4, P < 0.001). Corneal infiltrative events occurred in 0% of emmetropes and 2.9% of spectacle wearers and ranged from 2.4% to 7.5% in lens wearers.
Based on the outcomes, the researchers concluded that, under the conditions of this study, comfort and vision with some contemporary daily disposable contact lenses were indistinguishable from non-wearing emmetropes. Although the contact lens-wearing groups had rates of corneal infiltrative events that were not statistically different from the non-wearers, the study had insufficient power to permit robust conclusions in this respect.
So, have we come close to the endgame in contact lens wear? Well, likely not. However, this study suggests that we are getting quite a bit closer. We have developed contact lenses that actually "do nothing" (other than provide clear vision). Nice job contact lens industry, keep up the good work.
1. Lazon de la Jara P, Diec J, Naduvilath T, Papas EB. Measuring Daily Disposable Contact Lenses against Nonwearer Benchmarks. Optom Vis Sci. 2018 Dec;95(12):1088-1095.
OCULAR SURFACE UPDATE
Katherine M. Mastrota, MS, OD
2019 Eyelash Science Musings
As far back as I can remember, I have loved the science of magnets. I also love eyelashes. I also often think about makeup and the ocular surface. How are these things connected? Consider the following:
1. Magnet-assisted transfection (the process of deliberately introducing naked or purified nucleic acids into eukaryotic cells) is a transfection method that uses magnetic interactions to deliver DNA into target cells. Here, nucleic acids are associated with magnetic nanoparticles, and magnetic fields drive the nucleic acid-particle complexes into target cells, where the nucleic acids are released.1
2. Demodex mites reside in the eyelash follicle and, of course, have their own genetic makeup. Interestingly, sequencing the mites' mitochondrial DNA revealed different lineages that closely match the ancestral geography of their human hosts.2
3. Magnetic fields influence stem cell properties. For example, novel strategies utilizing magnetic nanoparticles (MNPs) and magnetic fields are being developed to enhance bone tissue engineering efficacy. Magnetic-cell strategies include cell labeling, targeting, patterning, and gene modifications. These new methods using magnetic nanoparticles and scaffolds with magnetic fields and stem cells increase the osteogenic differentiation, angiogenesis, and bone regeneration by two- and three-fold controls. For bone growth, potential clinical applications of magnetic nanoparticles and scaffolds with magnetic fields and stem cells include dental, craniofacial, and orthopedic treatments with substantially increased bone repair and regeneration efficacy.3
4. Now, commercially available, is eyeliner with magnetic particles in it used to affix magnetic eyelashes.
Wow. Could micro-magnetic eyeliner be absorbed and the use of magnetic eyeliner and magnetic lashes cause a transfection-type phenomenon of Demodex nucleotides into eyelash follicle cells? Alternately, could the liner/lash combination set up a magnetic field that could impact the lash stem cell niche and alter eyelash growth cycling? Or the limbal corneal stem cell niche? Or the goblet cell niche? I wonder….
Commonly Held Beliefs About Myopia That Lack a Robust Evidence Base
The purpose of this study was to subject a number of commonly held beliefs or areas of confusion in the myopia field to scientific scrutiny.
In this study, a collection of statements about myopia are provided with references to demonstrate that a section of the research or clinical community supports the statement. The topics under discussion are reviewed critically with reference to the literature.
According to the research, the following statements are considered to lack sufficient supporting data to be considered as evidence-based: low-dose (0.01%) atropine slows myopia progression; relative peripheral hyperopia leads to myopia development and progression in children; undercorrection slows myopia progression; percentage treatment effect remains constant with continuing treatment; percentage treatment effect applies across the progression range; hand-held digital devices contribute to the myopia epidemic; more time outdoors slows myopia progression; the impact of outdoor activity on myopia incidence is due to daylight; subclassifications for myopia are effective; and myopia is a condition with a negative dioptric number.
The authors concluded that there are many hypotheses proposed to explain phenomena in the myopia field. Caution should be exercised in adopting conjecture until a robust evidence base is provided in support.
Brennan NA, Cheng X. Commonly Held Beliefs About Myopia That Lack a Robust Evidence Base. Eye Contact Lens. 2018 Nov 7. [Epub ahead of print]