Each year in our September issue of Contact Lens Spectrum, we try to publish a “Top 10” list of sorts. That is, what are the Top 10 or so issues we face in the field of contact lenses. Some topics seem to stay the same, while others come and go. We would love to hear your feedback on this. What do you think are some of the Top 10 issues in contact lenses? Please email your feedback to us @ email@example.com.
Jason J. Nichols, OD, MPH, PhD
Allergan Files to FDA for Approval of Oculeve Intranasal Tear Neurostimulator
Allergan plc announced that it has filed with the U.S. Food and Drug Administration (FDA) the de novo application for the Oculeve Intranasal Tear Neurostimulator device. According to the FDA, this process provides a pathway for medical devices for which general and/or special controls provide a reasonable assurance of safety and effectiveness, but for which there is no legally marketed predicate device.
This handheld stimulator was investigated for temporarily increasing tear production upon activation in patients with dry eye disease due to decreased tear production. Recently Allergan announced that two pivotal trials of the Oculeve Intranasal Tear Neurostimulator each met their effectiveness endpoints.
EyeXam, a mobile eye care app with more than 1.5 million free downloads to date, launched a dry eye screening tool, now available within the EyeXam app, designed to provide dry eye sufferers an easy way to screen the severity of their condition on their mobile devices. The app also makes it easy for a user to search for a nearby eye doctor who can try to determine the cause of their symptoms and develop an appropriate treatment plan.
EyeXam incorporated the Ocular Surface Disease Index (OSDI) questionnaire into its mobile app enabling people to determine the severity of their dry eye condition by answering a series of simple questions about their symptoms. The EyeXam app also allows patients to search for a nearby eye doctor and is a convenient gateway to MyDryEyes.com, an educational web site designed to answer commonly asked questions about chronic dry eye (CDE).
EyeXam users are encouraged to have proactive and fruitful discussions with their eye doctors. The mobile app is designed so consumers, who are experiencing dry eye symptoms, can download the free app, take the dry eye quiz that doctors use and trust as a subjective measure of their patients' symptoms, and share the results with their doctor.
To learn more about EyeXam, visit www.eyexam.com online or the iTunes or Google Play stores on your smartphone or tablet.
The Educational Program Committee of the Global Specialty Lens Symposium invites the submission of abstracts for the Free Paper Section and the Scientific Poster Competition. Papers and posters related to presbyopia, keratoconus, corneal topography, post penetrating keratoplasty or related irregular corneal surface, myopia control, orthokeratology and lens care topics are welcome.
The GSLS will be held January 19-22, 2017 at The Rio Hotel in Las Vegas, Nevada. Visit www.GSLSymposium.com for more information. Web submissions only. Deadline for submissions is August 31, 2016.
Blanchard Contact Lenses released the cities and dates for their fall Beyond the Limbus Scleral Lens Workshop tour. The Beyond the Limbus workshops, in their sixth year, are a component of Blanchard University, Blanchard’s educational division.
Attendees can look forward to a high impact workshop, with well-prepared information, valuable hands-on experiences, takeaways that will ensure their success, and Blanchard’s commitment to ongoing support. Blanchard will also be discussing their new Onefit Asian design lenses, as well as XLC - the new Extra Limbal Clearance option that simplifies fitting of Onefit lenses even further.
Registrations are now being accepted for the following workshops:
September 11: Manchester, NH
October 2: New Orleans, LA
October 9: Scottsdale, AZ
October 16: Denver, CO
October 23: Atlantic City, NJ
October 30: San Antonio, TX
November 6: Newport Beach, CA
Practitioners wishing to attend a Beyond the Limbus workshop can register at www.blanchardlab.com, by calling (800) 367-4009, or by contacting their respective Blanchard sales representative. Space is limited and sessions fill up quickly.
ABB Optical Group announced that the UIW Rosenberg School of Optometry won the first University Education Challenge, a program hosted by ABB Optical and Paragon Vision Sciences to support the optometrists of tomorrow. The San Antonio-based school, which competed against six other colleges for the honor, received a $5,000 unrestricted educational grant as its prize.
UIW won based on the attendance and survey results of a webinar created and presented by third-year student Amy Belloli-Conner. Faculty members Dr. Farshid Amir and Dr. William Miller oversaw her efforts. Belloli-Conner's webinar focused on the importance of contact lens cleaning and compliance after physical activities such as mud runs, color runs and water slide adventures. ABB Optical and Paragon Vision Sciences also awarded $500 to Belloli-Conner.
Other schools that participated in the challenge included runner-up Indiana University School of Optometry, the New England College of Optometry, Pacific University College of Optometry, Salus University Pennsylvania College of Optometry, Southern College of Optometry, and the University of Missouri College of Optometry.
World Sight Day Challenge Celebrates 10th Anniversary
Optometry Giving Sight has launched its 10th annual fundraising campaign to help raise funds for people who are needlessly blind or vision impaired simply because they can’t access an eye exam and vision care provided by an optometrist. This year’s World Sight Day Challenge will focus on the need for effective, sustainable eye health initiatives for children and adolescents. The campaign will run from September 1st until October 31st. World Sight Day is Thursday October 13th.
For the past 10 years, thousands of Optometrists, their staff, patients, students and colleagues in industry have taken the World Sight Day Challenge by making a tax-deductible donation and / or by raising funds to help eliminate the backlog of uncorrected refractive error, estimated to affect more than 600 million people. Click to watch video.
Funds raised will help support Our Children’s Vision – a global campaign to bring better vision, and eye health services to 50 million children by 2020. This will be in addition to the ongoing support for Optometry Development programs, which train local people as optometrists.
Optometry Giving Sight has materials to help promote your involvement, lots of fun fundraising ideas, and information that you can share that shows how your practice’s donations are having an impact on the lives of people in need. To donate, or pledge your participation by selecting one of our Bronze, Silver, Gold or Platinum Award levels, please visit www.givingsight.org.
Bausch + Lomb, a leading global eye health company, announced that its 2015 interactive experience, encouraging South by Southwest (SXSW) Film + Interactive Festival attendees to "Get Their Blink On," was honored with a Gold SABRE Award for “Consumer Health Campaign of the Year.” The B+L Ultra Lens Lounge, featured at the festival, encouraged lens-wearing Millennials to visit their eye care professional and discuss how their screen-reliant lifestyle may be negatively impacting their vision, while offering a free one-month trial of Bausch + Lomb Ultra contact lenses.
Visitors to the Bausch + Lomb Ultra Lens Lounge were also invited to share their experience on their social media channels, using the campaign’s official hashtag #ULTRAUpgrade. Cali Lewis, host of GeekBeat.TV and tech influencer, produced a series of webisodes highlighting B+L Ultra contact lenses as a cutting–edge comfort and vision upgrade, while sharing her personal experience in switching to the lenses.
The annual North American SABRE awards, created by the public relations trade journal The Holmes Report, recognize superior achievement in branding reputation and engagement. The Zeno Group, B+L’s public relations agency, led the planning and execution of the campaign.
Assessment of biomechanical properties of the cornea is now a clinical as well as research reality in eye care. There have been so many unanswered questions in terms of how eyes respond to various influences that now are coming to light based upon assessment of individual and variable responses of the cornea to these elements.
In a recently published study, researchers looked at the biomechanical responses of the cornea to soft toric contact lens wear.1 They looked at 33 subjects who had no prior history of contact lens wear. Subjects were fit into a soft toric contact lens fabricated from comfilcon A. The Ocular Response Analyzer (Reichert Ophthalmics) was used to measure corneal hysteresis (CH) and corneal resistance factor (CRF). Additionally, Pentacam measurements (Oculus Inc.) were taken to determine central corneal thickness (CCT) and mean keratometric values (K mean). Measurements were taken prior to contact lens wear as well as at one week, one month and three months following fitting and lens wear. Results found that both CH and CRF were decreased significantly by one month following the initiation of contact lens wear (p= 0.013 and 0.017 respectively). CCT and K mean did not change significantly during the period of toric soft contact lens wear. The researchers concluded that corneal biomechanical properties can change following soft toric contact lens wear and that these changes may have implications with the use of such lenses.
Corneal biomechanical properties have wide ranging implications including glaucoma, corneal response to contact lens wear, kerato-refractive surgery, and corneal reshaping treatments and in a variety of corneal diseases – most notably keratoconus and other forms of corneal ectasia. Clinically available instruments have come to market including the Ocular Response Analyzer and the newly introduced Corvis system (Oculus Inc.). Clinicians will begin to introduce these technologies into their clinical armamentarium and will be able to better identify certain “at risk” patients for disease, as well as to assist in better predicting outcomes to surgical and other treatment modalities. Stay aware of this new and upcoming area of ophthalmic diagnostics.
1. Radaie-Moghadam S, Hashemi H, Jafarzadehpur E, Yekta AA, Khabazkhoob M. Corneal Biomechanical Changes Following Soft Toric Contact Lens Wear. J Ophthalmic Vis Res. 2016 April-June; 11(2):131-5.
OCULAR SURFACE UPDATE Katherine M. Mastrota, MS, OD, FAAO
The Patient’s Perspective
If I were questioned, I would say that most eyecare practitioners often find the management of dry eye patients a daunting task. Signs and symptoms for these individuals are mixed and patients are oft frustrated with the challenges, cost and duration of therapy. I was generally pleased to read a report in The Ocular Surface that studied the patients’ perspective on their dry eye disease.1
This cross-sectional study included 91 patients with dry eye disease. In addition to clinical evaluation, all patients completed a questionnaire to evaluate their perspectives on their disease. This included their satisfaction with understanding dry eye disease, their opinion on the ease of following doctors' advice, their opinion on the effectiveness of the treatment, their satisfaction with the eye care, and their general outlook on dry eye disease. Most of the patients included in the study were female. The average age of the patient was 54. The average patient in this subset of patients had been treated for 5 years. Ninety-three percent of the patients were satisfied with their understanding of dry eye disease, and 76% found it easy to follow their doctors' advice for dry eye disease management. Furthermore, 95% thought that the dry eye disease treatment had been helpful and 95% were satisfied with their eye care for dry eye disease. It must be noted however that in this same patient set, 52% of the patients were not optimistic regarding their dry eye disease.
Although this is a small study, it is encouraging that patients understand their disease and that our efforts in manipulating the natural course of the disease have a positive effect. It is important to note that although patient experiences with dry eye disease management was positive, the majority of patients did not have a similar outlook regarding the outcome of their disease. We still have work to do.
Crnej A, Kheirkhah A, Ren A, Mullins A, Lavric A, Suri K, Dana R. Patients' Perspectives on Their Dry Eye Disease. Ocul Surf. 2016 Jul 6. pii: S1542-0124(16)30081-7. doi: 10.1016/j.jtos.2016.06.001.
Impact of Lens Care Solutions on Protein Deposition on Soft Contact Lenses
The purpose of this study was to evaluate the effect of four contemporary lens care solutions on total protein, total lysozyme, and active lysozyme extracted from three contact lens materials.
Adapted contact lens wearers were recruited at three sites, and all subjects were randomly assigned to daily wear of either etafilcon A, galyfilcon A, or senofilcon A for 2 weeks. Four lens care solutions (Biotrue, Opti-Free PureMoist, RevitaLens OcuTec, and Clear Care) were used by each subject in random order with a new pair of lenses after a washout period between solutions of at least 4 days. After 2 weeks of daily wear, contact lenses were collected for analysis. Proteins were extracted from a subset of contact lenses (n = 568) and total protein, total lysozyme, and lysozyme activity were quantified using a modified Bradford assay, an enzyme-linked immunosorbent assay, and a micrococcal assay, respectively.
Higher levels of total protein were extracted from etafilcon A when used with Biotrue compared to other solutions (p = 0.0001). There were higher levels of total lysozyme extracted from galyfilcon A lenses when used with PureMoist than with Biotrue or Clear Care (p < 0.006). Higher total lysozyme was extracted from senofilcon A when used with RevitaLens OcuTec compared to Biotrue (p = 0.002). Lower lysozyme activity was recovered from senofilcon A lenses with RevitaLens OcuTec when compared to all other care solutions (all p < 0.004). When Biotrue, PureMoist, or RevitaLens OcuTec were used, higher total lysozyme was extracted from galyfilcon A compared to senofilcon A (p < 0.01). When RevitaLens OcuTec was used, higher levels of active lysozyme were extracted from galyfilcon A compared to senofilcon A (p = 0.02).
The researchers concluded that the ability of lens care solutions to remove protein from lenses varies depending upon the care solution composition and also the polymeric make-up of the contact lens material.
Babaei Omali N, Heynen M, Subbaraman LN, Papinski D, Lakkis C, Smith SL, Morgan PB, Berntsen DA, Nichols JJ, Jones LW; Performance of Contact Lens Solutions Study Group. Impact of Lens Care Solutions on Protein Deposition on Soft Contact Lenses. Optom Vis Sci. 2016 Jul 6. [Epub ahead of print]