5 Topic Commentaries

Restoring Visual Function in a Posttraumatic Cornea

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  Esen K. Akpek, MD

  Cornea and External Disease

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  Wilmer Eye Institute, Johns Hopkins Medicine

  20/200 is actually pretty good vision for a person who sustained such severe injuries. He was able to see the second big 'E' on the eye chart. He was able to walk around by himself. He was also able to see his wife's face for the first time.

  Source
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  Winston Chamberlain, MD, PhD

  Cornea and External Disease

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  Casey Eye Institute, Oregon Health & Science University

  It's quite remarkable how much reconstruction we can do in this part of the eye versus other parts of the eye. We can restore most, if not all the function to the eye.

  Source
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  Ula Jurkunas, MD

  Cornea and External Disease

  •

  Massachusetts Eye and Ear / Harvard Medical School

  Now we have this new data supporting that CALEC is more than 90 percent effective at restoring the cornea’s surface, which makes a meaningful difference in individuals with cornea damage that was considered untreatable.

  Source
• 

  Sunil K. Chauhan, PhD

  Corneal Immunology and Regenerative Medicine (Ophthalmology Research)

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  Schepens Eye Research Institute of Mass. Eye and Ear / Harvard Medical School

  Our results show that mesenchymal stem cells, in an inflamed environment, secrete high levels of HGF, which inhibit scar formation and restore corneal transparency. But if you silence the HGF expression, the stem cells lose their capacity to inhibit scar formation.

  Source
• 

  Leo Maguire, MD

  Corneal Transplantation

  •

  Mayo Clinic

  People who have the DMEK surgery recover really fast. I've had some people's vision restored to 20/20 or 20/25, with spectacle correction, a week after surgery.

  Source