Objective:
To describe the successful visual rehabilitation of a patient with corneal scarring using a scleral lens and topical losartan.
Approach:
- Case Description: A 25-year-old female with keratoconus developed a bacterial corneal ulcer post-corneal cross-linking, leading to scarring and neovascularization. She was fitted with a BostonSight Scleral lens and treated with topical losartan.
- Treatment Protocol: Topical losartan was administered 4 times daily, including instillation in the scleral lens reservoir to enhance drug delivery.
Key Findings:
- Best-corrected visual acuity improved from hand motion to 20/20 after scleral lens wear and topical losartan use.
- Scleral lens facilitated sustained exposure to topical losartan.
Interpretation:
The case describes the use of scleral lenses to improve visual acuity and deliver topical medications like losartan.
Limitations:
- Topical losartan is an off-label use for reducing corneal scarring and is not FDA approved for this purpose.
- No published guidelines exist for the duration of topical losartan therapy.
Conclusion:
The case highlights the potential benefits of scleral lenses in managing corneal scarring and suggests further investigation into the efficacy of topical losartan.
Sources:
This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.