Objective:

To highlight the importance of proper contact lens care and hygiene in preventing ocular adverse events, specifically corneal infiltrative events and microbial keratitis.

Key Findings:

• Contact lens wear accounts for 52% to 65% of newly diagnosed microbial keratitis cases, highlighting a significant public health concern.
• Sleeping in contact lenses is identified as the most significant risk factor for microbial keratitis, necessitating patient education.
• Different MPSs exhibit varying antimicrobial abilities against specific Gram-negative organisms, indicating the need for tailored recommendations.
• Disinfectants such as PAPB, PHMB, and Alexidine demonstrate superior effectiveness compared to MAPD-based solutions, suggesting a shift in clinical practice.

Interpretation:

The findings underscore the necessity for eyecare practitioners to recommend effective disinfecting solutions and emphasize adherence to proper contact lens hygiene to mitigate risks of ocular complications.

Limitations:

• The study's findings may not be generalizable to all contact lens users due to variations in individual practices, lens types, and environmental factors.
• The effectiveness of disinfectants may vary based on environmental factors not accounted for in the study, which could influence real-world application.

Conclusion:

Adhering to recommended contact lens care practices and using effective disinfecting solutions can significantly reduce the risk of corneal infiltrative events and microbial keratitis, emphasizing the need for patient compliance.